Does Kidney “Stuff”Work?

Kidney “Stuff” is a dietary supplement composed of a unique blend of simple, natural ingredients derived from whole foods specifically designed for people interested in supporting their kidney function. Many of the ingredients in Kidney “Stuff” have been used in traditional medicine for centuries for their health benefits. Additionally, numerous studies have linked the ingredients in Kidney “Stuff” with potential benefits for the kidneys. The proprietary blend combines these ingredients in the proper ratios which has aided many customers in accomplishing their health goals. The historic medicinal use and the recent studies conducted on the ingredients found in Kidney “Stuff” are summarized here. 

Real Cold Milled Flaxseed

Flaxseed is rich in α-linolenic acid (ALA), lignans, and fiber, and flaxseed has been associated with health benefits across the body’s systems including the kidneys, cardiovascular, and immune systems(1). Flaxseed was valued in ancient times in Egypt as both a food and medicine and is used in Ayurvedic medicine as an anti-inflammatory medicine(2). Flaxseed has been appreciated throughout history and Gandhi was once quoted, “whenever flaxseed becomes a regular food item among the people, there will be better health.”

Several studies have shown the beneficial effects of flaxseed on kidney parameters including in animal models of diabetic kidney disease, lupus nephritis, and polycystic kidney disease(1,3,4). In addition, flaxseeds contain omega-3 fatty acids which have been shown to reduce the risk of kidney failure(5).

Our Milled Flaxseed is RCM Flaxseed™ Real Cold Milled. The flax enters the process at room temperature, is milled at room temperature, and exits at room temperature. Furthermore, our proprietary milling method does not grind, crush or liberate oil like other processes, making our product very unique.

Concentrated Flax Hull Lignans

Flax hulls are the shell of flaxseed with the seed removed. Flax hulls are not typically found in flaxseeds purchased at the store, but they contain high concentrations of key phytonutrients called lignans. Lignans, also called secoisolariciresinol diglucosides (SDG), are polyphenol compounds that studies suggest may reduce the risk of lifestyle-related diseases including kidney disease. Studies in animal models have shown the beneficial effects of flax hull lignans on diabetes and kidney diseases including lupus nephritis(6). Lignans also show promise in reducing chronic inflammation, which underlies many chronic diseases including cardiovascular and kidney disease. Higher consumption of lignans is associated with reduced inflammatory markers in American adults(7). 

Despite the huge potential benefit of lignans, many foods contain relatively low levels. Flaxseed is the richest source of lignans in the plant kingdom, containing up to 800 times more than any other plant source and lignans are especially concentrated in flax hulls(1).  

Carrot Root Powder

In addition to being considered a cleansing food in traditional medicine, carrots contain a wide variety of vitamins and minerals important for kidney health including vitamins A, B, C, E, and K, as well as calcium, iron, and magnesium. Carrots are rich in the antioxidant beta-carotene. Antioxidants are used to inactivate reactive oxygen species to mitigate oxidative stress, an important factor in chronic kidney disease(8). Studies in animal models demonstrate that carrot root extracts have kidney-protective effects against kidney injury(9). 

White Kidney Bean Powder

Kidney beans do not only look like human kidneys, but they contain many amino acids, minerals, and vitamins that play key roles in supporting kidney health. Kidney beans have been used for centuries for health benefits in traditional medicine, particularly for diabetes control(10). More recently, studies have demonstrated the beneficial effects of kidney beans on biomarkers of kidney function in both diabetic and non-diabetic animals(10,11). The historic use of kidney beans in traditional medicine and our developing understanding of their mechanistic benefits through scientific research continue to support their use for kidney health.  

Bovine Kidney Powder

Glandular tissues have been used throughout history as food and nutritional supplements. Glandular is a term to describe animal glands and organ extracts that are consumed to nourish the corresponding human tissue. Many cultures traditionally consumed organs from animals to treat ailments. Bovine kidneys are highly similar to human kidneys in their biochemical composition. Bovine kidney powder contains many of the amino acids, vitamins, and minerals needed to nourish human kidneys.  

The bovine kidney powder in Kidney “Stuff” is a nutritional product made from superior ingredients; quality controlled to ensure optimum potency, safety, and efficacy and also has strict government procedures for licensing, auditing, and certification. It comes from animals grazed on rangelands that are known to be free of pesticides, antibiotics, and growth hormones.

Beetroot Powder

Beets are an excellent source of antioxidants and contain betanin which may promote kidney health. Betanin is a natural pigment responsible for the rich color of beets. Betanin has been shown to promote the expression of detoxifying enzymes in human cells(12). Another study demonstrated that beetroot powder has kidney-protective and blood glucose-lowering effects. These powerful results lead the authors of the study to advise daily consumption of beetroot powder for kidney patients(13). 

Importantly, sourcing high-quality beet powder is critical as betanin is a delicate molecule that is sensitive to light. The beet powder in Kidney “Stuff” is carefully sourced and transported to ensure the highest quality.

Defatted Wheat Germ

Defatted wheat germ contains many amino acids and minerals to support kidney health. A recent study found that wheat germ supplementation improves kidney function in animals with kidney disease by reducing oxidative stress(14). 

Why is Kidney “Stuff” the best kidney supplement?

The unique, proprietary blend of ingredients in Kidney “Stuff” provides these ingredients in appropriate ratios to support kidney health, and no other product like it is available on the market. The ingredients are carefully sourced, transported, and stored to maximize quality. These ingredients are sourced from the best suppliers across the world and Kidney “Stuff” is manufactured in the United States. Kidney “Stuff” is free of additives, pesticides, and preservatives.  

Who should use Kidney “Stuff”?

Kidney “Stuff” is designed for anyone interested in improving their kidney health. Numerous studies and years of research have shown the ingredients in Kidney “Stuff” may help support overall kidney health and function.* Kidney “Stuff” is not recommended for people who are pregnant or nursing. Consult your physician before beginning any dietary supplement. 

* These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

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1. Goyal, A., Sharma, V., Upadhyay, N., Gill, S. & Sihag, M. Flax and flaxseed oil: an ancient medicine & modern functional food. Journal of Food Science and Technology vol. 51 Preprint at https://doi.org/10.1007/s13197-013-1247-9 (2014).

2. Soni, R. P., Katoch, M., Kumar, A. & Verma, P. Flaxseed – composition and its health benefits. Res. Environ. Life Sci. rel 9, 310–316 (2016).

3. Al-Bishri, W. M. Favorable effects of flaxseed supplemented diet on liver and kidney functions in hypertensive Wistar rats. J Oleo Sci 62, (2013).

4. al Za’Abi, M., Ali, H. & Ali, B. H. Effect of flaxseed on systemic inflammation and oxidative stress in diabetic rats with or without chronic kidney disease. PLoS One 16, (2021).

5. Hu, J., Liu, Z. & Zhang, H. Omega-3 fatty acid supplementation as an adjunctive therapy in the treatment of chronic kidney disease: A meta-analysis. Clinics vol. 72 Preprint at https://doi.org/10.6061/clinics/2017(01)10 (2017).

6. Imran, M. et al. Potential protective properties of flax lignan secoisolariciresinol diglucoside. Nutr J 14, (2015).

7. Eichholzer, M. et al. Urinary lignans and inflammatory markers in the US National Health and Nutrition Examination Survey (NHANES) 1999-2004 and 2005-2008. Cancer Causes and Control 25, (2014).

8. Diaz-Ricart, M. et al. Endothelial damage, inflammation and immunity in chronic kidney disease. Toxins vol. 12 Preprint at https://doi.org/10.3390/toxins12060361 (2020).

9. da Silva Dias, J. C. Nutritional and Health Benefits of Carrots and Their Seed Extracts. Food Nutr Sci 05, (2014).

10. Kyznetsova, M. Y. et al. Effect of aqueous extract from Phaseolus vulgaris pods on lipid peroxidation and antioxidant enzymes activity in the liver and kidney of diabetic rats. J Appl Pharm Sci 5, (2015).

11. A, I. et al. EFFECTS OF RAW AND COOKED AQUEOUS AND METHANOL EXTRACTS OF PHASEOLUS VULGARIS (KIDNEY BEANS) ON RENAL FUNCTION IN ALBINO WISTAR RATS. Universal Journal of Pharmaceutical Research (2020) doi:10.22270/ujpr.v5i3.408.

12. Krajka-Kuźniak, V., Paluszczak, J., Szaefer, H. & Baer-Dubowska, W. Betanin, a beetroot component, induces nuclear factor erythroid-2-related factor 2-mediated expression of detoxifying/antioxidant enzymes in human liver cell lines. British Journal of Nutrition 110, (2013).

13. El-Sheikh, N. A., Nasef, A. Z. & Othman, N. Y. Potential Therapeutic Effects of Beet Root) Beta Vulgaris, L.) Pomace on Nephropathy Diabetic Rats. Alexandria Science Exchange Journal 40, (2019).

14. Kandeil, M. A. M., Hassanin, K. M. A., Mohammed, E. T., Safwat, G. M. & Mohamed, D. Sh. Wheat germ and vitamin E decrease BAX/BCL-2 ratio in rat kidney treated with gentamicin. Beni Suef Univ J Basic Appl Sci 7, (2018).